Effective prevention for patients at increased caries risk*,^

Colgate Duraphat 2800 ppm Fluoride Toothpaste provides 20% reduction in DMFS increment2,#

Colgate Duraphat 5000 ppm Fluoride Toothpaste prevents cavities by arresting and reversing primary root and early fissure caries lesions1,3-5

76%

of patients prefer the taste of Duraphat 5000 ppm#,1

It’s a matter of taste…
Improving adherence in increased caries risk patients

of consumers agree that taste is an important factor when using a toothpaste**

of patients would prefer to use
Duraphat 5000 ppm toothpaste if it was prescribed ongoing†,#,1

of patients prefer
brushing with Duraphat 5000 ppm#,1

Prescribing a product with a preferred taste may be
important to enhance patient adherence

Adherence is important in driving
patient use of medicines

Adherence is an active behaviour, where your patient takes part in their care and decide when and whether to follow your advice and instructions7

Clinical Impact

Economic Impact

Failure to take medicines correctly and derive the optimal benefits has significant economic implications:9,10

• £300m lost annually due to medicine wastage

• Every year, over £500m in health gains foregone in just five therapeutics areas***

Prescribe Colgate Duraphat 5000 ppm Fluoride Toothpaste to support adherence

Consider prescribing up to 6 packs depending on the recall interval of the patient

Clinical evidence for Duraphat toothpaste supports its continued use to optimise the prevention of caries2-6 Consider the date of the patient’s next recall appointment and prescribe enough tubes to last until then (1 tube lasts approximately 1 month^^)

Frequently asked questions when prescribing

Download our Frequently Asked Questions by Dentists and Community Pharmacists to support you when prescribing Colgate Duraphat

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Scotland
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N.Ireland

Be confident prescribing Colgate® Duraphat®,
the brand your patients know and trust††

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References

* Colgate® Duraphat® 5000 ppm high fluoride toothpaste for patients ≥ 16 years at increased caries risk.
^ Colgate® Duraphat® 2800 ppm high fluoride toothpaste for patients ≥ 10 years at increased caries risk.
# Compared to generic 5000 ppm high fluoride toothpaste.
† for 4 weeks or more.
**Colgate UK Consumer Survey on Cosmetic Toothpaste. 504 participants. Feb 2020
^^Usage as according to the summary of product characteristics.
††YouGov Omnibus for Colgate® UK, data on file June 2015. Claim applies only to the Colgate® brand.
*** These five therapeutic areas include asthma, type 2 diabetes, hypertension, schizophrenia and statins for primary prevention and secondary prevention of cardiovascular diseases3

References:
1. Data on file. Preference Survey. January 2020 (n=82).
2. Baysan A et al. Caries Res 2001;35:41-46.
3. Biesbrock AR et al. Community Dent Oral Epidemiol 2001;29:382-389.
4. Ekstrand et al. Caries Res 2013;47:391–8.
5. Schirrmeister JF et al. Am J Dent 2007;20. 212-216.
6. Ekstrand et al. 2008 Gerod 2008; 25:67-75.
7. https://www.podiatrytoday.com/blogged/what-difference-between-adherence-versus-compliance-patient-behavior.
8. US Surgeon General Koop CE. Keynote address. In: Improving Medication Compliance. Proceedings of a Symposium. Reston, Va. National Pharmaceutical Council. 1985.
9. Dept. Health and Rt. Hon. Earl Howe. 8 August, 2011. Action on medicine wastage and improving medicine use. https://www.gov.uk/government/news/action-on-medicine-wastage-and-improving-medicine-use.
10. Evaluation of the scale, cause and costs of waste medicine. Final report. York health Economics Consortium and School of Pharmacy, University of London. November 2010.

Prescribing Information

Colgate Duraphat® 2800 ppm Fluoride Toothpaste – Name of the medicinal product: Duraphat® 2800 ppm Fluoride Toothpaste. Active ingredient: Sodium Fluoride 0.619 %w/w (2800 ppm F-). Indications: For the prevention and treatment of dental caries (coronal and root) in adults and children 10 years of age and over. Dosage and administration: Use daily instead of normal toothpaste. Apply a 1cm line of paste across the head of a toothbrush and brush the teeth thoroughly for one minute morning and evening. Spit out after use; for best results do not drink or rinse for 30 minutes. Contraindications: Individuals with known sensitivities should consult their dentist before using. Not to be used in children under 10 years old. Special warnings and precautions for use: Not to be swallowed. Undesirable effects: When used as recommended there are no side effects. Legal classification: POM. Marketing authorisation number: PL00049/0039. Marketing authorisation holder: Colgate-Palmolive (U.K.) Ltd. Guildford Business Park, Midleton Road, Guildford, Surrey, GU2 8JZ. Recommended retail price: £5.10 (75ml tube). Date of revision of text: January 2015.

Colgate® Duraphat® 5000 ppm Fluoride Toothpaste – Name of the medicinal product: Duraphat® 5000 ppm Fluoride Toothpaste. Active ingredient: Sodium Fluoride 1.1%w/w (5000ppm F-). 1g of toothpaste contains 5mg fluoride (as sodium fluoride), corresponding to 5000ppm fluoride. Indications: For the prevention of dental caries in adolescents and adults 16 years of age and over, particularly amongst patients at risk from multiple caries (coronal and/or root caries). Dosage and administration: Brush carefully on a daily basis applying a 2cm ribbon onto the toothbrush for each brushing. 3 times daily, after each meal. Contraindications: This medicinal product must not be used in cases of hypersensitivity to the active substance or to any of the excipients. Special warnings and precautions for use: An increased number of potential fluoride sources may lead to fluorosis. Before using fluoride medicines such as Duraphat, an assessment of overall fluoride intake (i.e. drinking water, fluoridated salt, other fluoride medicines – tablets, drops, gum or toothpaste) should be done. Fluoride tablets, drops, chewing gum, gels or varnishes and fluoridated water or salt should be avoided during use of Duraphat Toothpaste. When carrying out overall calculations of the recommended fluoride ion intake, which is 0.05mg/kg per day from all sources, not exceeding 1mg per day, allowance must be made for possible ingestion of toothpaste (each tube of Duraphat 500mg/100g Toothpaste contains 255mg of fluoride ions). This product contains Sodium Benzoate. Sodium Benzoate is a mild irritant to the skin, eyes and mucous membrane. Undesirable effects: Gastrointestinal disorders: Frequency not known (cannot be estimated from the available data): Burning oral sensation. Immune system disorders: Rare (≥1/10,000 to <1/1,000): Hypersensitivity reactions. Legal classification: POM. Marketing authorisation number: PL00049/0050. Marketing authorisation holder: Colgate-Palmolive (U.K.) Ltd. Guildford Business Park, Midleton Road, Guildford, Surrey, GU2 8JZ. Recommended retail price: £7.99 (51g tube). Date of revision of text: February 2015.